Urinary tract infections (UTIs) continue to be one of the most common infectious diseases. So, in the United States, the incidence of UTI is about 1000 cases per 100,000 population per year, and according to data obtained in the USA, this group of diseases causes 7 million visits and more than 1 million emergency calls to doctors annually. The financial component of this problem is also significant, the cost of treatment of which in the United States alone reaches $ 2 billion annually.
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UTIs are also leading among nosocomial infections, accounting for about 40% of their total number. Bacteriuria develops in 25% of patients with a urethral catheter for more than a week, and subsequently, the risk of its occurrence is 5% per day. According to American data, the occurrence of nosocomial UTI increases the cost of treatment by 100-500 US dollars.
Despite a widespread misconception, the structure of the causative agents of most infectious diseases does not undergo significant changes over time. At the same time, the changes taking place in the principles of treatment of such diseases are associated with various factors, including deepening knowledge about their pathogenesis, identifying previously unknown pathogens, the emergence of new, more effective drugs, as well as the development of resistance of microorganisms to the used antimicrobial agents [6,7]. In the context of UTI, the latter factor is of the greatest importance.
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Very important is the question of the duration of ciprofloxacin treatment for various UTIs. These data are presented in table 3. Table 3. Duration of treatment with ciprofloxacin for various UTIs
|UTI||Duration of therapy (days)|
|Acute Uncomplicated Gonorrhea||1-3|
|Complicated gonorrhea, complicated UTI||7-14|