The Lisinopril is one of the most important remedies for high blood pressure. It belongs to the group of so-called ACE inhibitors and is mostly used in tablet form. Possible side effects include drowsiness, headache and cough. Children, pregnant women and nursing mothers should only take medicines containing lisinopril after consulting their doctor. Here you can read everything you need to know about Lisinopril.
This is how Lisinopril works
The body has a sophisticated system for regulating blood pressure. If more energy is required, the blood pressure is automatically increased; however, it is regulated downwards during periods of rest.
If this system is disrupted, it can lead to increased blood pressure. Most of the time, those affected do not notice it, and the high blood pressure gradually creeps up . The small vessels, such as those found in the eyes and kidneys , are particularly affected by the constantly increasing pressure. If high blood pressure remains undetected for a long time, it can have serious consequences such as loss of vision and kidney dysfunction.
To prevent such consequential damage, the blood pressure must be normalized. This can sometimes be achieved with weight loss and more exercise, but often blood pressure-lowering medication must also be taken.
Lisinopril is one of these drugs. As a representative of the group of “ACE inhibitors”, lisinopril reduces the formation of vasoconstricting messenger substances (angiotensin-II) and increases the formation of vasodilator messenger substances (bradykinin). This can effectively lower blood pressure, which also relieves the heart.
Uptake, breakdown and excretion of Lisinopril
After ingestion via the mouth (orally), the active substance is incompletely absorbed from the intestine into the blood. It is distributed in the body and is ultimately excreted unchanged via the kidney.
When is Lisinopril used?
The areas of application (indications) of Lisinopril include:
- High blood pressure (hypertension)
- Short-term treatment of a heart attack
What are the long term side effects of lisinopril?
Common long term side effects of lisinopril include:
- Extreme tiredness
- Runny nose
- Low sex drive
Serious side effects can also occur. If you have any of these side effects, call your doctor right away:
- Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Trouble breathing or swallowing
- Signs of infection, such as fever, sore throat, and chills
- Yellowing of the skin or eyes
- Lightheadedness or fainting
- Chest pain
Commonly, i.e. in one to ten percent of those treated, lisinopril causes side effects such as drowsiness, headache , cough , gastrointestinal complaints and low blood pressure (hypotension).
More rarely, allergic reactions, changes in behavior and circulatory disorders in the extremities of the fingers occur during the course of treatment .
This is how Lisinopril is used
The active substance lisinopril is mostly used in the form of tablets. The dosage is usually between ten and 80 milligrams – depending on the area of application and the severity of the respective disease. The dose must therefore be set individually for each patient.
Children, adolescents and patients with renal impairment receive a reduced dose.
The tablets only need to be taken once a day, preferably with a large glass of water and always at the same time of day.